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22 Strain: Effects, Medical Benefits, and Growing Guide

22 Strain: Effects, Medical Benefits, and Growing Guide
The 22 strain, also known as “Double-Deuce,” is a sativa-leaning hybrid with 70% sativa and 30% indica genetics. It is a cross between the iconic OG Kush and Jack Herer, two renowned strains that bring both uplifting and body-relaxing qualities to the table. The result? A strain that offers a unique combination of energetic, cerebral stimulation and a subtle, calming body high.
Known for its diamond-shaped buds and densely packed forest-green leaves, 22 is both visually stunning and potent, boasting a THC content of 24%. Its pine, sage, and floral aromas, combined with a spicy, chemical flavor, make it a sensory delight, perfect for daytime use when you need a boost of creativity or energy.
But what really sets 22 apart is its ability to manage a variety of medical conditions, including anxiety, depression, ADHD, PTSD, and chronic pain. With these benefits and its powerful effects, it’s no wonder this strain has gained a loyal following among both recreational and medical users.

Cannabinoid & Terpene Profile: The Chemistry Behind 22 Strain’s Potency

The 22 strain isn’t just known for its energetic effects—it packs a punch with its cannabinoid and terpene profile, making it a versatile option for both recreational and medicinal users.
22 Strain: Effects, Medical Benefits, and Growing Guide

Terpenes in 22

The Terpene profile of 22 also plays a significant role in its effects:

Myrcene

Known for its sedative properties, myrcene helps create the subtle relaxation that complements the strain’s energetic effects. It may help ease muscle spasms and offer mild pain relief.

Limonene

This citrus-scented terpene adds to the strain’s uplifting effects, making it ideal for managing stress, anxiety, and depression. It also enhances mood, contributing to the euphoria commonly reported by users.

Beta-Caryophyllene

A spicy, peppery terpene, beta-caryophyllene provides anti-inflammatory benefits and works to alleviate chronic pain and muscle spasms.
These cannabinoids and terpenes work together to create 22’s signature uplifting yet calming experience. With its high THC content and rich terpene profile, the strain delivers a balanced experience that’s both mentally stimulating and physically relaxing.

Aroma, Flavor, and Appearance: A sensory Experience

The 22 strain is as rich in aroma and flavor as it is in effects. From the moment you break apart its dense, diamond-shaped buds, you’re greeted with an array of earthy, piney, and floral fragrances that are both fresh and grounding. The aroma is dominated by the sage and pine notes, giving it an herbal and slightly spicy scent, while subtle hints of floral sweetness come through to balance the experience.
When it comes to flavor, 22 offers a similarly complex profile. On the inhale, you’ll taste pine and a distinct chemical sharpness, which is often attributed to the limonene and beta-caryophyllene terpenes. The spicy, sage-like flavors linger on the exhale, making it a bold and refreshing strain to consume.
22 Strain: Effects, Medical Benefits, and Growing Guide
Visually, 22 stands out with its tree-shaped buds that are tightly packed with forest-green leaves. The buds are dense, almost resembling diamonds, and are coated with a layer of frosty trichomes, giving the plant a sparkling, crystalline appearance under the light.
This combination of aromas, flavors, and visual appeal makes 22 not only a potent strain but also one that provides a full sensory experience, appealing to cannabis connoisseurs who appreciate more than just the high.

Effects: Uplifting, Creative, and Energizing

The 22 strain is celebrated for its powerful, sativa-dominant effects, making it an ideal choice for daytime use. Its high is fast-acting and starts with an intense cerebral rush, quickly boosting mood and providing a burst of euphoria and creativity. Users often describe feeling energized and more talkative, making this strain great for social settings, creative projects, or even exercise.
22 Strain: Effects, Medical Benefits, and Growing Guide

Creativity & Focus

Many users report heightened creativity and focus, thanks to the uplifting qualities of limonene. Whether you need to power through a task or find inspiration, the 22 strain delivers mental clarity without overwhelming you with sedation.

Euphoria & Happiness

The strain induces strong feelings of happiness and euphoria, keeping spirits high throughout the experience. This makes it a go-to strain for managing conditions like depression, as the mood-boosting effects can be immediate and long-lasting.

Talkative & Sociable

In social settings, 22 can help you become more talkative and engaged, perfect for those looking to reduce social anxiety and feel more at ease during interactions.
However, because of its high THC content (24%), the effects can become intense if overconsumed. Some users may experience dry mouth, dry eyes, anxiety, or even a rapid heartbeat. It’s best to start with a small dose, especially for those who are sensitive to THC.
Despite its uplifting effects, 22 also carries a calming body high that helps alleviate physical discomfort without causing couch-lock. This balance makes it a favorite among users looking for energy and relief from chronic pain or fatigue.

Growing 22 strain: Tips for Cultivators

Growing 22 strain can be a moderately challenging endeavor, but the rewards make the effort worthwhile. Its sativa-dominant genetics, along with its OG Kush and Jack Herer lineage, give it strong growing characteristics, making it a high-yield plant under the right conditions. Here’s what you need to know to get the best results:
Indoor Growth
When grown indoors, 22 typically reaches heights between 30 to 60 inches (76 to 152 cm). It is a compact yet high-yielding plant, making it manageable for smaller grow spaces. Yields can range from 10.5 to 14 ounces per square meter, so ensure your space is well-ventilated and properly lit.
Outdoor Growth
Outdoors, 22 can grow much taller, reaching heights between 60 to 80 inches (152 to 203 cm). This strain thrives in Mediterranean-like climates with lots of sunshine, warmth, and moderate humidity. You can expect an outdoor yield of approximately 400 grams (14 ounces) per plant under optimal conditions.
Temperature and Humidity

Like many cannabis strains, 22 prefers a warm environment with humidity levels kept under 70% to avoid mold or bud rot. During the early stages of growth, keep the humidity higher (around 60-70%), and gradually lower it as the plant approaches the flowering stage to about 50-55%

Flowering Time
The flowering stage for the 22 strain typically takes between 60 to 70 days (around 10 weeks). If grown outdoors, you can expect to harvest in October if you’re in the Northern Hemisphere. As a photoperiod strain, 22’s flowering is triggered by changes in light exposure, so make sure to adjust light cycles accordingly if you’re growing indoors.
Yields
Thanks to its Jack Herer parentage, 22 is a high-yielding strain, especially when given enough space and care. Expect dense, resin-rich buds with a strong pine and sage aroma.
22 Strain: Effects, Medical Benefits, and Growing Guide

FAQs about 22 Strain

What is the THC content of 22?
The 22 strain has a THC content of approximately 24%, making it a potent option for experienced users. Its high THC levels contribute to the strain’s energetic, uplifting effects, but it also means that users, particularly beginners, should be cautious with their dosage to avoid overwhelming effects like anxiety.
What medical conditions can 22 help treat?
The 22 strain is reported to help with several medical conditions, including:
  • Chronic Fatigue Syndrome (CFS): Its uplifting effects, driven by limonene and CBG, make it a great strain for combating fatigue.
  • PTSD & ADHD: The mood-enhancing properties of limonene can help manage anxiety and focus issues.
  • Depression: The strain’s euphoric effects can improve mood and reduce symptoms of depression.
  • Muscle Spasms & Chronic Pain: Thanks to beta-caryophyllene and THC, 22 helps manage pain and muscle tension.
Is 22 suitable for beginners?
Due to its high THC content, beginners should approach 22 with caution. It is best to start with a small dose to gauge tolerance, as overconsumption can lead to side effects such as anxiety, dry mouth, or a rapid heartbeat.
What are the primary effects of 22 strain?
The effects of the 22 strain are energetic, creative, and uplifting. Users often experience a quick onset of euphoria followed by a light body relaxation, making it perfect for daytime activities or tasks that require focus and creativity. However, at higher doses, the relaxing effects may become more pronounced.
What are the common side effects of 22 strain?
While 22 has many uplifting benefits, it can also cause some side effects, particularly if consumed in large doses. These include:
  • Dry mouth
  • Dry eyes
  • Anxiety
  • Headache
  • Thirst
  • Rapid heartbeat
How does 22 compare to other sativa-dominant hybrids?

The 22 strain is often favored for its balance between mental clarity and physical relaxation. Unlike some sativa-dominant strains that can be overly stimulating, 22 provides a steady stream of energy while keeping the body calm, making it ideal for daytime use without the overwhelming buzz of other sativa-heavy strains.

How long does 22 take to flower, and what are the yields?

22 strain typically takes 60-70 days to flower, with outdoor harvests occurring in October. When grown indoors, yields can reach between 10.5 to 14 ounces per square meter, while outdoor plants may yield around 400 grams (14 ounces) per plant.

22 Strain: Effects, Medical Benefits, and Growing Guide

Looking to explore the therapeutic benefits of strains like 22?

Get your medical marijuana card today and consult  Marijuana Specialist Near Me to find the right strain and dose for your needs.

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A Picture of Richard Koffler MD

Article Written By

Richard Koffler, MD

NPI Number- 1467557264

About Richard Koffler, MD

  • Dr. Koffler is a Physiatrist, specializing in Physical Medicine & Rehabilitation.
  • Graduated from the Sackler School of Medicine at Tel Aviv University in 1993 Dr. Koffler completed a one-year internship in internal medicine at Roosevelt Hospital in New York City.
  • Residency in Physical Medicine and Rehabilitation at the Rusk Institute at NYU Medical Center in New York City. Board certified in 1998.
  • Trained in acupuncture at Helms Medical Institute at UCLA His medical practice incorporates proven conventional western medicine integrating eastern alternative practices.
  • Medical Director of several medical clinics in NYC, Stamford CT, and Miami Beach, FL.
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